Context-Specific Procedures for the Diagnosis of Human Schistosomiasis – A Mini Review
نویسندگان
چکیده
Schistosomiasis is a parasitic disease caused by trematode blood flukes of the genus Schistosoma , affecting over 250 million people mainly in tropics. Clinically, can present itself with acute symptoms, stage which relatively more common naive travellers originating from non-endemic regions. It also develop into chronic disease, outcome depending on species involved, duration and intensity infection several host-related factors. A range diagnostic tests available to determine infection, including microscopy, antibody detection, antigen detection using Point-Of-Care Circulating Cathodic Antigen (POC-CCA) test Up-Converting Particle Lateral Flow Anodic (UCP-LF CAA) test, as well Nucleic Acid Amplification Tests (NAATs) such real-time PCR. In this mini review, we discuss these different procedures explore their most appropriate use context-specific settings. With regard endemic settings, approaches are described based suitability for individual diagnosis, monitoring control programs, determining elimination public health problem eventual interruption transmission. For summarize suitable imported cases, either or chronic. Additionally, options disease-specific clinical presentations genital schistosomiasis neuro-schistosomiasis included. Finally, specific role within research settings described, controlled human model studies. conclusion, have requirements stressing importance well-considered decision procedure.
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ژورنال
عنوان ژورنال: Frontiers in tropical diseases
سال: 2021
ISSN: ['2673-7515']
DOI: https://doi.org/10.3389/fitd.2021.722438